| Abbreviation | Definition |
| ALPR | Automated license plate recognition |
| ALTS | Automated Licensing and Taxation System |
| CDLIS | Commercial Driver License Information System |
| CMV | Commercial motor vehicle |
| CVIEW | Commercial Vehicle Information Exchange Window |
| CVISN | Commercial Vehicle Information Systems and Networks |
| CVSA | Commercial Vehicle Safety Applications (Kentucky) |
| DVR | Digital video recorder |
| EWD | Extended Weight [Coal] Decal |
| FHWA | Federal Highway Administration (USDOT) |
| FMCSA | Federal Motor Carrier Safety Administration (USDOT) |
| FMCSR | Federal Motor Carrier Safety Regulations |
| HQ | Headquarters |
| ICC | Interstate Commerce Commission |
| ID | Identification |
| IFTA | International Fuel Tax Agreement |
| IIS | Intelligent Imaging Systems |
| IR | Infrared |
| IRP | International Registration Plan |
| ISS | Inspection Selection System |
| ISSES | Integrated Safety and Security Enforcement System |
| ITS | Intelligent transportation systems |
| JPO | Joint Program Office (U.S. DOT) |
| KIT | Kentucky Intrastate Tax |
| KTC | Kentucky Transportation Center (Univ. of Kentucky) |
| KVE | Kentucky Vehicle Enforcement |
| KYU | Kentucky Use |
| L&I | Licensing and Insurance |
| LTCCS | Large Truck Crash Causation Study |
| MCMIS | Motor Carrier Management Information System |
| MCSIP | Motor Carrier Safety Improvement Program |
| NCIC | National Crime Information Center |
| NLETS | National Law Enforcement Telecommunication System |
| OCR | Optical character recognition |
| OOS | Out of service |
| ORNL | Oak Ridge National Laboratory |
| PRISM | Performance and Registration Information Systems Management |
| RITA | Research and Innovative Technology Administration (USDOT) |
| SAFER | Safety and Fitness Electronic Record |
| SM | Safe Miles |
| SSRS | Single-State Registration System |
| TFSS | Truck Fleet Safety Survey |
| USDOT | US Department of Transportation |
| VMT | Vehicle miles traveled |
| VNTSC | John A. Volpe National Transportation Systems Center (USDOT) |
| WDT | Weight distance tax |
| WIM | Weigh in motion |